Bicarbonate has been commonly used in the dialysate bath to correct metabolic acidosis, and has been used preferentially over acetate for patients with marked hemodynamic instability due to sepsis or other causes, particularly patients requiring vasopressor support. Side Effects. Sodium bicarbonate (Alka-Seltzer Heartburn Relief) is a drug used to treat excess stomach acid and heartburn. Not to exceed 8 mEq/kg/day. 120 to 200 mEq/m2/day diluted in maintenance IV fluids of 3000 mL/m2/day; titrate to maintain urine pH between 6 and 7. Dr. Pritchard writes as a San Francisco biology expert for a prominent website and thoroughly enjoys sharing the knowledge he has accumulated. Parenteral: Most experts only allow for its use when tissue perfusion and ventilation are maximized and the arterial pH is 7.1 or lower. As with any drug, if you are pregnant or nursing a baby, seek advise of a health professional before using this product. Medically reviewed by Drugs.com. diagnosis or treatment. or Children up to 6 years of age—Dose must be determined by your doctor. If acid-base status is available, dosages should be calculated as follows: SODIUM BICARBONATE (SOE dee um; bye KAR bon ate) is an antacid. Rapid correction of the deficit can cause hypokalemic cardiotoxicity in patients who are potassium-depleted, tetany in patients with renal failure or hypocalcemia or congestive heart failure in patients with poor left ventricular function due to the excess sodium load from this medication). Copyright Policy In nonemergency cases of metabolic acidosis, sodium bicarbonate is mixed with other intravenous fluids and introduced gradually to the patient over a four- to eight-hour period, Drugs.com explains. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. Milder side effects include increased thirst, gas and stomach discomfort, according to MedlinePlus, a service of the National Institutes of Health. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Sodium bicarbonate is an antacid that neutralizes stomach acid. Rapid IV Cardiac arrest Initially 44.6-100 mEq. Children 6 to 12 years of age—The dose is 520 mg. Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more likely to occur if it is taken: in large doses, for a long time, or by patients with kidney disease. One gram provides 11.9 mEq (mmol) each of sodium and bicarbonate. Sodium bicarbonate is removed by hemodialysis. used as a substitute for professional medical advice, In tablet form, sodium bicarbonate can treat heartburn in children if given in a dose of 520 mg. Privacy Policy Moderate metabolic acidosis: 325 to 2000 mg orally 1 to 4 times a day. Circulatory overload and hypernatremia can occur when large volumes of hypertonic sodium bicarbonate are given. 2010 sodium-bicarbonate-antidote-343749 Drugs Drugs sodium bicarbonate (Antidote) 2010 alka-seltzer-original-aspirin-citric-acid-sodium-bicarbonate-341994 Drugs May continue at a rate of 44.6-50 mEq every 5-10 min if necessary. As an effervescent powder, children from 6- to 12-years-old require 1 to 1.9 g, or 1/4 to 1/2 tsp., of sodium bicarbonate in a glass of cold water. If the increase in urinary pH is inadequate, increasing the sodium bicarbonate in solution to 100 to 150 mEq/L may result in further alkalinization of the urine. Other possible side effects include systemic alkalosis and/or CNS acidosis. For patients suffering from heartburn or indigestion, sodium bicarbonate is given as a effervescent powder, noneffervescent powder and in tablet form, MayoClinic.com reports. 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